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IMMUNOGLOBULIN ALPHA-CHAINS
Descriptors Found:
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DeCS
Descriptor
English
:
Immunoglobulin alpha-Chains
Descriptor
Spanish
:
Cadenas alfa de Inmunoglobulina
Descriptor
Portuguese
:
Cadeias alfa de Imunoglobulina
Synonyms
English
:
Immunoglobulins, alpha-Chain
Tree Number:
D12.776.124.486.485.114.619.026.515
D12.776.124.486.485.705.500.350
D12.776.124.790.651.114.619.026.515
D12.776.124.790.651.705.500.350
D12.776.377.715.548.114.619.026.515
D12.776.377.715.548.705.500.350
Definition
English
:
The class of heavy chains found in
IMMUNOGLOBULIN A
. They have a
molecular weight
of approximately 58 kDa and contain about 470 amino acid residues arranged in four domains and an oligosaccharide component bound covalently to their Fc fragment constant region.
Indexing Annotation
English
:
gammopathy: coordinate
IMMUNOGLOBULIN ALPHA-CHAINS
(IM) with
PARAPROTEINEMIAS
(IM) but consider also
HYPERGAMMAGLOBULINEMIA
(IM) or ALPHA-CHAIN DISEASE(IM), follow text; DF: IG ALPHA CHAIN
Pharmacological Action:
Immunologic Factors
History Note
English
:
2006 (1976)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
contraindications
drug effects
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
poisoning
radiation effects
toxicity
therapeutic use
ultrastructure
urine
Record Number:
30358
Unique Identifier:
D007137
Occurrence in VHL
:
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